Subjective cognitive impairment: Towards early identification of Alzheimer disease
نویسندگان
چکیده
منابع مشابه
Mild cognitive impairment represents early-stage Alzheimer disease.
BACKGROUND Mild cognitive impairment (MCI) is considered to be a transitional stage between aging and Alzheimer disease (AD). OBJECTIVE To determine whether MCI represents early-stage AD by examining its natural history and neuropathologic basis. DESIGN A prospective clinical and psychometric study of community-living elderly volunteers, both nondemented and minimally cognitively impaired, ...
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Introduction: Mild Cognitive Impairment (MCI), a disorder of the elderly people, is difficult to diagnose and often progresses to Alzheimer Disease (AD). Temporal region is one of the initial areas, which gets impaired in the early stage of AD. Therefore, auditory cortical evoked potential could be a valuable neuromarker for detecting MCI and AD. Methods: In this study, the thresholds of...
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OBJECTIVE To characterize the course of cognitive decline during the prodromal phase of Alzheimer disease. DESIGN Longitudinal cohort study with up to 16 years of observation. PARTICIPANTS Older persons from 2 studies underwent annual clinical evaluations that included cognitive function testing and clinical classification of mild cognitive impairment, dementia, and Alzheimer disease. At ba...
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BACKGROUND AND PURPOSE Subjective cognitive complaints (SCCs) are very common in patients with Parkinson's disease (PD). However, the relationship between SCCs and objective cognitive impairment is still unclear. This study aimed to determine whether SCCs are correlated with objective cognitive performance in patients with PD. METHODS Totals of 148 cognitively normal patients, 71 patients wit...
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The growth in ageing population in recent years has resulted in increasing prevalence of dementia. Alzheimer Disease (AD) is the most common cause of dementia [1] particularly, among the aged population. The most accurate way to diagnose AD is to analyze histopathological changes showing amyloid plaques and neurofibrillary bundles. However, in practice, the diagnosis is often based on clinical ...
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ژورنال
عنوان ژورنال: Neurología (English Edition)
سال: 2016
ISSN: 2173-5808
DOI: 10.1016/j.nrleng.2013.02.011